Javid Moslehi, MD
I am a cardiologist and myocyte biologist. My clinical focus is cardio-oncology and cardio-immunology. My clinical interests overlap with my laboratory focus, where we are investigating the mechanistic underpinnings of cardiovascular sequelae of novel targeted and immune-based cancer therapies. I have previously directed similar cardio-oncology programs at Brigham and Women’s Hospital/Dana-Farber Cancer Institute (2009-2014) and Vanderbilt (2014-2021) before coming to UCSF. In each case, I have created clinical and research programs involving multiple clinicians, and researchers, as well as robust fellowship programs interested in training the next generation of physician-scientists. Our group works closely with industry and regulatory bodies (e.g., US FDA) to bring new therapies to cardiovascular disease.
Juan Qin, PhD
Dr. Juan Qin is an Assistant Researcher in Dr. Moslehi’s Lab at UCSF. She is passionate about understanding the immune-cardiac interactions in inflammatory heart disease and cardiotoxicity of cancer therapy, hoping to identify novel safer therapies to treat patients. In the Moslehi Lab, her research is multifaceted and sits at the interface of Cardiology, Oncology, Immunology, Bioinformatics, and Biology. Juan earned her Ph.D. in Cell Biology and Cancer Biology from Nankai University in 2017. During her three years of postdoctoral training at UCLA, she focused on understanding cardiac repair after injury.
Shaoyi Zhang, MD, PhD
Dr. Shaoyi Zhang is a postdoctoral fellow in Moslehi’s laboratory. He is trained as a gastrointestinal and oncology surgeon in China where he received his MD (2014). Shaoyi also completed a Ph.D. at Université Paris-Sud in Paris, France from 2014-2018 in Professor Guido Kroemer’s laboratory where he studied cell death mechanisms in inflammatory disease and cancer. As a surgeon and physician-scientist, his clinical research interests included the microbiome and gut homeostasis in chronic gastrointestinal disorders. He moved to UCSF in the Section of Cardio-Oncology and Immunology and is dedicated to deciphering the crosstalk between heart and gut microbiome in an effort to understand the mechanisms of cardiac inflammatory disease including immunotherapy cardiotoxicities. He hopes to develop future therapeutic targets in cardio-oncology. Dr. Zhang is a member of the European Academy of Tumor Immunology (EATI)
Matthew Fleming, MD, PhD
Dr. Matthew Fleming is a post-doctoral fellow in the Moslehi laboratory where he studies the role of Bruton's Tyrosine Kinase (BTK) inhibitors in the development of cardiac arrhythmias. Matthew performed his undergraduate studies in biochemistry at the State University of New York College at Geneseo prior to beginning his graduate studies at Yale University in the Department of Cellular and Molecular Physiology in the lab of Dr. Len Kaczmarek. Matthew’s graduate research focused on ion channel modulation by kinases and mechanisms by which dysregulation of these signaling pathways results in pediatric epilepsy. After completion of his Ph.D., Matthew attended Columbia University’s College of Physicians and Surgeons where he earned his MD as a member of the first class of students in a 3 year Ph.D. to MD/Ph.D. track. After graduation, he began his post-graduate medical training at Vanderbilt University in Internal Medicine as a member of the Harrison Society, Vanderbilt’s Physician-Scientist Training Program. Matthew continued his training as a fellow in Cardiology at Vanderbilt and is currently a Fellow in Cardio-Oncology. He is currently co-mentored by Dr. Moslehi at UCSF and Dr. Dan Roden at Vanderbilt.
Sehej Bindra
Sehej Bindra is a student at UC Berkeley majoring in biochemistry. Before joining the Moslehi Lab, Sehej studied sensory physiology under the mentorship of Dr. Pidgeon, conducted design-based research at the Berkeley School of Education, and worked at startups in industries from edtech, social networks, and biotechnology. At the Moslehi Lab, Sehej is combining his experience in both software development and biology to contribute to the Cardio-Oncology research at this lab.
Radhe Patel
Radhe Patel is an undergraduate student pursuing a double degree in Public Health and Molecular and Cell Biology at UC Berkeley. In the past, Radhe has research experience in anti-aging with a focus on the positive influences of natural products on mTOR gene pathways at the Kennedy Lab at NUS. She also has experience in the Medina Lab at UCSF CHORI working on targeting cholesterol in mice through the Tmem55b gene pathway. Radhe also works as a part-time Medical Assistant at a Urology Clinic and intends to pursue medicine in the future and is especially passionate about maternal and child health. In her free time, she enjoys dancing, running, and spending time with friends.
Claire Rammel
Claire Rammel is an undergraduate at UC Berkeley pursuing a double degree in Molecular and Cell Biology and Psychology. Before joining the Moslehi Lab, Claire worked in the CALM Lab at UC Berkeley under Dr. Sheri Johnson studying Goal-Based Learning and Habit in the context of OCD. Claire also works for the Research Resilience Program in the Department of Molecular and Cell Biology at UC Berkeley where she holds workshops for undergraduates to meet researching faculty, helps undergraduates find research positions and overall supports the undergraduate research community. In the future Claire hopes to pursue a career as a scientist and researcher.
Mandar Aras, MD, PhD
Dr. Mandar Aras is an Assistant Professor of Medicine at UCSF. He is an advanced heart failure/transplant cardiologist who is interested in the intersection of cardio-oncology, immunology, and heart failure. He is involved in multiple clinical research projects investigating the use of machine learning in disease detection, understanding cardiac arrhythmias in amyloidosis, and the role of genetic polymorphisms in chemotherapy-induced cardiomyopathy. Dr. Aras serves on the American Heart Association cardio-oncology subcommittee. Dr. Aras obtained his combined medical and graduate degrees from the University of Pittsburgh School of Medicine as part of a combined MD/PhD program. Dr. Aras completed an internal medicine residency at Duke University, and fellowships in cardiology and advanced heart failure/transplant cardiology at UCSF.
Amy Lin, MD, PhD
Dr. Amy Erica Lin is an Assistant Clinical Professor of Medicine at UCSF. Dr. Lin’s clinical and research focus is on cardio-oncology, immunology and clonal hematopoiesis of indeterminate potential (CHIP) and heart disease. Dr. Lin obtained her medical and graduate degrees from the University of Toronto combined MD/PhD Program and Department of Medical Biophysics. Dr. Lin completed internal medicine residency at the University of Toronto, followed by cardiology fellowship at Brigham and Women’s Hospital and post-doctoral fellowship at the Dana Farber Cancer Institute and Brigham and Women’s Hospital as an American Society of Hematology (ASH) and an American College of Cardiology (ACC)/Merck Research Fellow.
Amir Munir, MD
Amir Munir, MD is a current Cardiology Fellow at UCSF. He earned his bachelor's degree in Chemistry at Washington University in St Louis, and his MD at Case Western Reserve University School of Medicine. He completed his Internal Medicine Residency at Brigham and Women’s Hospital in Boston. During medical school, Amir worked in the lab of Saptarsi Haldar, MD studying the role of BET bromodomains in vascular smooth muscle activation. He was subsequently awarded the Sarnoff Fellowship in Cardiovascular Research and spent a year in the lab of Eric Olson, Ph.D. at UT Southwestern. At UTSW, he helped characterize several previously unknown microproteins in putative lncRNAs found in skeletal muscle and cardiomyocytes, including microproteins integral to calcium handling, fatty acid oxidation, and the mitochondrial electron transport chain. He plans to pursue a career as a physician-scientist studying the interplay of cardiology, oncology, and immunology. Outside the lab and hospital, he enjoys hiking, exploring San Francisco, and cheering on his Cleveland sports teams.
Alan Gutierrez
Alan is a third-year medical student at Yale School of Medicine and current Sarnoff Fellow visiting the Moslehi lab. He received his B.A. in Biochemistry from Vassar College in 2018. There, he conducted research on Wingless signaling regulation in Drosophila melanogaster in the Kennell lab. In addition, he was a part of the First Generation 9, a sociological research team that investigated the experiences of first generation college students at a liberal arts institution, under the guidance of Dr. Eréndira Rueda. He was a research associate at the Broad Institute prior to matriculation to YSM. He worked with Dr. Steven Reilly as a part of the ENCODE Consortium Functional Characterization Center’s efforts to develop and apply next-generation non-coding CRISPR screens. As a result, he helped optimize HCR-FlowFISH—a novel technology that identifies cis-regulatory elements in the genome. He is broadly interested in cardiothoracic surgery and T cell immunology. He will be studying myocarditis and is looking forward to the discoveries ahead.
Lylybell Zhou
Lylybell Zhou is a Clinical Research Coordinator (CRC) for the UCSF Division of Cardiology, mainly working in the Section of Cardio-Oncology and Immunology. She graduated from the University of Florida with a Bachelor of Science in Medical Geography. As an undergraduate, she was a research assistant in the lab of Dr. Daniel Kopinke, working on the role of Hedgehog signaling in intramuscular fat infiltration; additionally, she worked with Dr. Jason K. Blackburn, authoring an honors thesis on the spatial-genomic associations of Brucella spp. in Kazakhstan. As a CRC at UCSF, she is responsible for supporting existing and new clinical studies that will help better understand cardiovascular complications in cancer patients and survivors. She looks forward to working with the UCSF Cardio-Oncology team and contributing to their exciting research efforts. In the future, she hopes to pursue a career as a physician-scientist.
Jiaqi Li, MB, BChir
Jiaqi graduated from the University of Cambridge School of Medicine, UK in 2023. She is currently working as a House officer in St Thomas’ Hospital in London. Jiaqi is interested in Cardiology and Oncology, and the interface between these two specialties. She had previously worked at the Karolinska Institutet with Dr. Evren Alici looking at engineering NK cells for immunotherapy as an Amgen Scholar. She had also worked with Dr. Claire Martin at the Royal Papworth Hospital in building a risk prediction model for modelling the risk of permanent pacemaker implantation in patients undergoing TAVR. Jiaqi is passionate about translational and clinical research and is excited to be part of the Moslehi lab. She hopes to become a cardiologist one day!